منابع مشابه
Genetic Variations and Gastric Cancer
Background: Gastric cancer (GC) has an apparent hereditary component. However, in a large fraction of gastric cases, no known genetic syndrome or family history can be identified, suggesting the presence of ‘missing heritability’ in GC etiology. Genome-wide association studies (GWAS) and traditional candidate gene studies have both led to the identification of multiple replicable common genetic...
متن کاملGenetic Variations and Gastric Cancer Risk
Gastric cancer used to be the leading cause of cancer deaths in the world until the 1980 when it was overtaken by lung cancer.1 Nowadays, stomach cancer is the second leading cause of cancer death in both sexes worldwide. In spite of worldwide global decrease, in 2020 (using computing models), the prevalence of gastric cancer is expected to rise in Portugal, for both sexes (Globocan). Most pati...
متن کاملGenetic variations at 8q24 and gastric cancer susceptibility: A meta-analysis study
BACKGROUND Published data on the association between genetic variants on the 8q24 chromosome and gastric cancer (GC) susceptibility are inconclusive. Here we present a meta-analysis designed to evaluate the relationship between 8q24 variants (single nucleotide polymorphisms (SNPs) labeled rs6983267 and rs1447295) and risk of developing GC. METHODS A literature search was performed using studi...
متن کاملGenetic Instability in Gastric Cancer
Gastric cancer remains a worldwide burden as a second leading cause of cancer death in both sexes (Globocan, 2011; Nobili et al., 2011). Although its incidence is in decline in developed countries, it is still the fourth most common malignancy in the world, behind cancers of the lung, breast, colon, and rectum (Globocan, 2011). The fall in its incidence is attributed mainly to the decline of th...
متن کاملGenetic predisposition to gastric cancer.
African states the overall incidence is only 5 Evidence for a genetic predisposition to gastric cancer per 100 000. In Europe, incidence rates are comes from both epidemiological studies and case between 20 and 40 per 100 000, and females have reports of gastric cancer families. Systematic caseabout half the male gastric cancer risk.1 control and cohort analyses of gastric cancer patients Appro...
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ژورنال
عنوان ژورنال: Gastrointestinal Tumors
سال: 2015
ISSN: 2296-3774,2296-3766
DOI: 10.1159/000431265